Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pituitary hyperplasia.

E Horvath1

  • 1St. Michael's Hospital, Department of Pathology, University of Toronto, Ontario, Canada.

Pathology, Research and Practice
|September 1, 1988
PubMed
Summary
This summary is machine-generated.

Human pituitary tissue studies reveal hyperplasia of adenohypophysial cells, a rare cause of pituitary hypersecretory syndromes. This non-neoplastic cell proliferation can stem from various regulatory peptide imbalances or external factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of hypoxia-inducible factor-1alpha (HIF-1alpha) in pituitary tumours.

Histology and histopathology·2003
Same author

Increased nuchal translucency and decreased fetomaternal transfusion after chorionic villus sampling.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2003
Same author

Additive neuroprotective effect of Ketanserin and Ipsapirone on the hippocampal damage after transient forebrain ischemia in the Mongolian gerbil.

Neuroscience letters·2003
Same author

Pituitary adenoma in Carney complex: an immunohistochemical, ultrastructural, and immunoelectron microscopic study.

Ultrastructural pathology·2003
Same author

Composite somatotroph--ACTH-immunoreactive pituitary adenoma with transformation of hyperplasia to adenoma.

Pituitary·2002
Same author

Pulse and continuous oral norfloxacin treatment of experimentally induced Escherichia coli infection in broiler chicks and turkey poults.

Acta veterinaria Hungarica·2002
Same journal

Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review.

Pathology, research and practice·2026
Same journal

Ras signalling in infectious disease pathology: Mechanisms, tissue damage, and clinical implications.

Pathology, research and practice·2026
Same journal

CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.

Pathology, research and practice·2026
Same journal

Multifactorial pathophysiology of varicocele: Integrating hemodynamic, oxidative, and endocrine mechanisms.

Pathology, research and practice·2026
Same journal

Comparative pathophysiology and pathology of transient ischemic attack, ischemic stroke, and reperfusion injury: Mechanistic and therapeutic perspectives.

Pathology, research and practice·2026
Same journal

Taraxerol targets the HIF1A-NEK6 axis to block TDE-mediated M2 macrophage polarization and inhibits NSCLC progression.

Pathology, research and practice·2026
See all related articles

Area of Science:

  • Endocrinology
  • Pathology
  • Human Pituitary Research

Background:

  • Pituitary hypersecretory syndromes can be caused by rare lesions.
  • Non-neoplastic proliferation of adenohypophysial cell types is a potential underlying cause.
  • Factors influencing this proliferation include hypothalamic peptides, dopaminergic regulation, and iatrogenic causes.

Purpose of the Study:

  • To provide conclusive evidence of hyperplasia in various human adenohypophysial cell types.
  • To explore the role of adenohypophysial hyperplasia as a cause of pituitary hypersecretory syndromes.
  • To discuss the histological characteristics and differential diagnosis of adenohypophysial hyperplasia.

Main Methods:

  • Morphologic study of a large number of human pituitary tissues.

Related Experiment Videos

  • Histological examination, including diffuse and nodular hyperplasia.
  • Reticulin network examination using silver staining techniques for differential diagnosis.

    • Main Results:

    • Conclusive evidence of hyperplasia in various adenohypophysial cell types was found.
    • Adenohypophysial hyperplasia can be diffuse or nodular.
    • Silver staining of the reticulin network aids in differential diagnosis.

    Conclusions:

    • Adenohypophysial hyperplasia is a significant finding in human pituitary tissues.
    • This hyperplasia is a potential cause of pituitary hypersecretory syndromes.
    • The study discusses the histological features and the potential for hyperplasia to progress to adenoma.