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Updated: Mar 2, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

[Cutaneous leukocytoclastic vasculitis: about 85 cases].

Amina Aounallah^1,2, Aicha Arouss^1,2, Najet Ghariani^1,2

¹Université du Centre, Tunisie.

The Pan African Medical Journal

|May 24, 2017

Summary

Leukocytoclastic vasculitis has diverse causes, including systemic diseases and infections. Identifying the underlying cause is crucial for effective treatment and managing outcomes.

Keywords:

Cutaneous leukocytoclastic vasculitis causes evolution

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Published on: May 31, 2017

Area of Science:

Dermatology
Immunology
Internal Medicine

Background:

Leukocytoclastic vasculitis (LCV) is a condition with poorly understood clinical features, causes, and outcomes.
Understanding LCV's epidemiology and clinical presentation is essential for diagnosis and management.

Purpose of the Study:

To investigate the epidemiological, clinical, etiological, and evolutionary characteristics of leukocytoclastic vasculitis.
To identify factors influencing the acute and chronic outcomes of LCV.

Main Methods:

A cross-sectional study involving 85 patients diagnosed with LCV.
Data collected from medical records between January 2000 and December 2013.
Analysis of epidemiological, clinical, paraclinical, and etiological data.

Main Results:

The average patient age was 47.65 years, with a female predominance (53 women, 32 men).
Cutaneous manifestations were primarily vascular purpura (88.2%).
Common causes included systemic diseases (51%), infections (20%), and neutrophilic dermatoses (14.5%). A cause remained undetected in 35.3% of cases.
Recent infection and drug intake predicted acute outcomes, while antinuclear antibodies and cryoglobulinemia correlated with chronic evolution.

Conclusions:

Leukocytoclastic vasculitis presents with a wide array of underlying causes.
Prompt identification of the etiology is imperative for optimal therapeutic management.
Factors like infection, drug use, antinuclear antibodies, and cryoglobulinemia are significant in predicting LCV outcomes.