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Spontaneous insertion of an IS2 element into the promoter region of the lac operon
P De Togni1, E S Fox, S Morrissey
1Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111.
Plasmid
|September 1, 1988
Abstract:
A spontaneous mutation in pUC18 has revealed the insertion of a chromosomal insertion sequence (IS)2 element into the promoter region of the lac operon. The IS2 insertion site, at the pentanucleotide sequence TCGAG, is unlike previously described junctional sequences.