Cryogenic transmission electron microscopy: the technique of choice for the characterization of polymeric
Adrianus C Laan1, Antonia G Denkova2
1Department of Radiation Science and Technology, Delft University of Technology, Delft, the Netherlands. a.c.laan@tudelft.nl.
EJNMMI Research
|May 24, 2017
Abstract:
This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying, demonstrating the importance of choosing the proper method.


