[Necrotic oophoritis due to cytomegalovirus]

In a 54-year-old woman with malignant lymphoma, cytomegalovirus oophoritis was disclosed at autopsy. The virus, which is recognized by its typical nuclear inclusions, reaches the cortical stroma of the ovaries and causes zones of necrosis there. Its presence is confirmed by ultrastructural and immunohistochemical examination. The real frequency of ovarian involvement is difficult to evaluate since histological examination of ovaries is not routinely performed at autopsy. As far as we know the present case is the seventh detailed observation of cytomegalovirus oophoritis published in the literature.