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Esophagus

Esophagus

The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...

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Updated: Mar 2, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

Eosinophilic Esophagitis in a Kitten.

Julie Pera¹, Douglas Palma¹, Taryn A Donovan¹

¹From the Hope Advanced Veterinary Center, Rockville, Maryland (J.P.); and the Animal Medical Center, New York, New York (D.P., T.D.).

Journal of the American Animal Hospital Association

|May 24, 2017

Summary

This summary is machine-generated.

A rare case of eosinophilic esophagitis (EoE) in a kitten was successfully treated with dietary changes. This condition, characterized by esophageal inflammation, highlights the importance of biopsy for diagnosis and diet in management.

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Area of Science:

Veterinary Medicine
Gastroenterology
Pathology

Background:

Eosinophilic esophagitis (EoE) is an uncommon esophageal inflammatory condition.
It is rarely reported in feline species.
Diagnosis requires histopathologic confirmation and exclusion of other causes.

Observation:

A 4-month-old kitten presented with chronic regurgitation and failure to thrive.
Radiography and esophagoscopy revealed esophageal dilatation and mucosal lesions.
Histopathology showed severe, chronic, hyperplastic eosinophilic and mastocytic esophagitis.

Findings:

Eosinophilic infiltrates were prominent (mean 29.8 eosinophils/HPF), confirming eosinophilic esophagitis (EoE).
Dietary modification with a hydrolyzed diet led to significant clinical improvement.
Glucocorticoids did not provide additional benefit.
Repeat histopathology indicated near resolution of eosinophilic infiltration.

Implications:

This case highlights the importance of esophageal biopsies for diagnosing EoE in kittens.
Dietary modification is an effective treatment strategy for feline EoE.
Early diagnosis and appropriate management can lead to favorable outcomes in affected kittens.