Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Primary Motives: Sleep, Sex, and Pain Avoidance01:24

Primary Motives: Sleep, Sex, and Pain Avoidance

6.2K
Primary motives such as sleep, sex, and pain avoidance are crucial drivers of behavior in humans and animals. These motives ensure survival, reproductive success, and overall well-being by prompting actions that meet essential bodily needs.
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
6.2K
Understanding Sleep01:11

Understanding Sleep

1.7K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.7K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

8.4K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.4K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

487
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
487
Analgesia and Pain Management01:25

Analgesia and Pain Management

2.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.4K
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

708
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
708

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Time-restricted eating and metabolic health: implications for nutritional strategies and weight loss.

Frontiers in nutrition·2026
Same author

Sleep continuity and stress physiology are associated with non-inflammatory variation in lymphocyte counts.

Sleep medicine·2026
Same author

Environmental determinants and inequitable exposure may reshape future projections of obstructive sleep apnea burden.

Environmental pollution (Barking, Essex : 1987)·2026
Same author

Eyes-Closed Resting-State fMRI After Sleep Deprivation: A Vigilance-Sensitive Window.

Journal of sleep research·2026
Same author

Autonomic Gating of Ripple Mode Selection at Sleep Onset.

Neuroscience bulletin·2026
Same author

Exploring the genetic overlap between obstructive sleep apnea and prostate cancer.

Journal of the National Cancer Center·2026

Related Experiment Video

Updated: Mar 2, 2026

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
09:03

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Published on: March 28, 2025

1.2K

The interfaces between vitamin D, sleep and pain.

Daniela Leite de Oliveira1, Camila Hirotsu2, Sergio Tufik1

  • 1Department of PsychobiologyUniversidade Federal de São Paulo, São Paulo, Brazil.

The Journal of Endocrinology
|May 25, 2017
PubMed
Summary

Vitamin D may improve sleep and reduce pain sensitivity. Supplementation combined with good sleep habits could help manage sleep disorders and chronic pain conditions like fibromyalgia.

Keywords:
hyperalgesiapainsleepvitamin D

More Related Videos

Polygraphic Recording Procedure for Measuring Sleep in Mice
08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

25.5K
Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K

Related Experiment Videos

Last Updated: Mar 2, 2026

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
09:03

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Published on: March 28, 2025

1.2K
Polygraphic Recording Procedure for Measuring Sleep in Mice
08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

25.5K
Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K

Area of Science:

  • Endocrinology
  • Neuroscience
  • Sleep Medicine

Background:

  • Vitamin D is crucial for bone health and influences various biological processes.
  • Sleep and pain perception are complex functions regulated by the central and peripheral nervous systems.
  • Sleep deprivation and pain, particularly hyperalgesia, are increasingly linked to vitamin D levels.

Purpose of the Study:

  • To explore the relationship between vitamin D, sleep, and pain.
  • To investigate vitamin D's potential role in modulating nociceptive sensitivity and sleep-wake cycles.
  • To assess the therapeutic potential of vitamin D supplementation for sleep disorders and chronic pain.

Main Methods:

  • Review of existing studies on vitamin D, sleep, and pain mechanisms.
  • Analysis of the correlation between vitamin D levels and conditions like fibromyalgia and rheumatic diseases.
  • Examination of vitamin D's proposed action on sleep and pain regulatory pathways.

Main Results:

  • Vitamin D levels are inversely correlated with painful conditions.
  • Poor sleep efficiency and sleep disorders are associated with altered vitamin D values.
  • Evidence suggests vitamin D influences both sleep regulation and pain perception.

Conclusions:

  • Vitamin D may play a role in regulating sleep and pain.
  • Vitamin D supplementation, alongside sleep hygiene, shows therapeutic promise for sleep disturbances and chronic pain.
  • Further research is warranted to fully elucidate vitamin D's impact on these interconnected health aspects.