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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
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Artificial Ureter in Patients with Extensive Ureteral Damage
Mohammad Yazdani1, Amir Javid2, Mehrdad Mohammadi Sichani1
1Isfahan University of Medical Sciences, Isfahan, Iran.
Urology Journal
|May 25, 2017
Summary
Subcutaneous nephron-vesical bypass (SNVB) offers a safe and effective solution for extensive ureteral damage when other methods fail. This permanent artificial ureter avoids the need for frequent exchanges, providing a durable alternative to nephrostomy tubes.
Area of Science:
- Urology
- Surgical Innovation
- Reconstructive Surgery
Background:
- Ureteral reconstruction is challenging, especially after failed bowel or bladder substitution.
- Loss of significant ureteral length necessitates advanced surgical solutions.
Purpose of the Study:
- To evaluate the efficacy and safety of subcutaneous nephron-vesical bypass (SNVB) for ureteral substitution.
- To assess SNVB in managing ureteral defects of diverse etiologies.
Main Methods:
- Seventeen SNVB procedures were performed using an artificial ureter (AU) comprising a silicone tube within a PTFE covering.
- The AU was tunneled subcutaneously, with proximal renal and distal bladder connections.
Main Results:
- Follow-up ranged from six months to ten years.
- One AU removal due to hematuria and one reoperation for urinary leakage were noted.
- The procedure was safe and effective in the majority of patients.
Conclusions:
- SNVB presents a safe and viable alternative to temporary nephrostomy tubes.
- The AU is a permanent device requiring no exchange, suitable for various ureteral injuries.
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