[Solid pseudopapillary neoplasms of the pancreas].

Area of Science:

• Oncology
• Gastroenterology
• Surgical Pathology

Background:

• Solid pseudopapillary neoplasm (SPN) is an exceptionally rare pancreatic tumor, predominantly affecting young females (median age 28).
• First described by Virginia Frantz in 1959, SPN was initially termed papillary cystic tumor of the pancreas.

Purpose of the Study:

• To retrospectively analyze the incidence of SPN in patients undergoing pancreatic surgery.
• To evaluate clinical presentation, diagnostic methods, surgical outcomes, and recurrence rates of SPN.

Main Methods:

• Retrospective analysis of pancreatic tumor resections between 2006-2015.
• Inclusion of clinical data, imaging (CT, MRI, PET/CT, endosonography), tumor markers, histology, and follow-up information.
• Surgical procedures included left-sided pancreatectomy and pylorus-preserving pancreaticoduodenectomy.

Main Results:

• SPN was diagnosed in 5 female patients out of 454 operated cases.
• Tumors were located in the pancreatic tail (4 cases) or head (1 case).
• One patient experienced postoperative bleeding; no pancreatic fistulas or recurrences were observed during follow-up.

Conclusions:

• SPN is a rare pancreatic neoplasm with low malignant potential, primarily in young women.
• Radical surgical resection is the sole curative treatment for SPN.
• SPN generally carries a favorable prognosis, with surgical management demonstrating effective oncological outcomes.