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Related Concept Videos

Osteoclasts in Bone Remodeling01:31

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Bone Cells and Tissue01:30

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Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
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Compact Bone01:27

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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Classification of Bones

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The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
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Analysis and Imaging of Osteocytes
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Cauliflower-Like Shaped Osteoma.

Tetsuya Okaneya1, Akihiro Ogino, Miho Nakamichi

  • 1Department of Plastic and Reconstructive Surgery, Toho University Omori Medical Center, Tokyo, Japan.

The Journal of Craniofacial Surgery
|May 25, 2017
PubMed
Summary
This summary is machine-generated.

A rare, cauliflower-like skull osteoma was observed in the occipital region of a 66-year-old male. Chronic stimulation is suspected as the cause of this unusual benign tumor morphology.

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Area of Science:

  • Neurosurgery
  • Pathology
  • Oncology

Background:

  • Skull osteomas are common, benign bone tumors that typically present with slow, continuous growth.
  • While often arc-shaped, osteomas can exhibit varied morphologies, necessitating detailed case studies for understanding.
  • The occipital region is a less common site for osteoma development, making such cases noteworthy.

Observation:

  • A 66-year-old male presented with a 50-year history of a growing occipital mass.
  • The mass, resected due to increased discomfort, displayed a rare, pedunculated, cauliflower-like shape attached to the skull.
  • The patient had no history of trauma or infection that could explain the unusual morphology.

Findings:

  • Pathological examination confirmed the diagnosis of osteoma.
  • The tumor's unique cauliflower-like morphology in the occipital region is a rare presentation.
  • Absence of trauma or infection suggests chronic stimulation as a potential etiological factor for the morphology.

Implications:

  • This case highlights the diverse morphological spectrum of skull osteomas.
  • Understanding the factors contributing to rare osteoma morphologies can aid in diagnosis and surgical planning.
  • Further research into chronic stimulation as a cause for osteoma's unusual shapes is warranted.