Related Experiment Video

Updated: Mar 1, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.5K

Central Hematocrit Levels in Fetal Malnourished Term Infants

Kerem Ertaş1, Özgül Salihoğlu, Emrah Can

  • 1*Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Training and Research, Hospital †Department of Pediatrics, Bağcilar Training and Research, Hospital, Istanbul, Turkey.

Journal of Pediatric Hematology/Oncology
|May 25, 2017
PubMed

Insights

Fetal malnutrition in newborns is linked to higher central hematocrit levels. Optimal fetal nutrition may prevent adult chronic diseases, highlighting the importance of monitoring neonatal hematocrit in appropriate for gestational age infants.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Hematology

Background:

  • Fetal malnutrition is a significant risk factor for developing chronic diseases later in life.
  • Optimal fetal nutrition is crucial for potentially preventing these adult-onset conditions.
  • Understanding neonatal health indicators associated with fetal malnutrition is essential.

Purpose of the Study:

  • To investigate the hematocrit levels in term, appropriate for gestational age (AGA) neonates diagnosed with fetal malnutrition.
  • To compare hematocrit values between malnourished and well-nourished AGA neonates.

Main Methods:

  • The study included 80 term AGA neonates, divided into a fetal malnutrition group and a control group of well-nourished neonates.
  • Central venous hematocrit levels were measured 4 hours after birth.
  • Maternal risk factors were also analyzed for both groups.

Main Results:

  • Fetal malnutrition group had significantly lower Clinical Assessment of Nutritional Status scores.
  • Despite no differences in gestational age or maternal factors, hematocrit levels were significantly higher in the fetal malnutrition group (59.53±5.094) compared to the control group (51.33±2.740).
  • P-value < 0.0001 indicated statistical significance.

Conclusions:

  • Term appropriate for gestational age neonates with fetal malnutrition exhibit significantly higher central hematocrit levels compared to their well-nourished counterparts.
  • These findings underscore the importance of assessing hematocrit in neonates with suspected fetal malnutrition.
Abstract

More Related Videos

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.6K
Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System07:34

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System

Published on: May 5, 2018

12.4K

Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
3.7K
Erythropoiesis01:14

Erythropoiesis

Red blood cells  (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia,...
6.3K
Overview of Hematopoiesis01:20

Overview of Hematopoiesis

Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
10.6K
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
2.5K
Hematopoiesis01:21

Hematopoiesis

The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
9.4K