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Intraocular pressure in exfoliation syndrome
1Department of Ophthalmology, University of Pennsylvania School of Medicine, Philadelphia.
Acta Ophthalmologica. Supplement
|January 1, 1988
Summary
Exfoliation syndrome (EX) can lead to glaucoma and elevated intraocular pressure (IOP). Patients with EX have a higher risk of developing increased IOP over time compared to those without the condition.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Ocular Health
Background:
- Exfoliation (EX) syndrome is often an incidental finding in general ophthalmology practices.
- Understanding the incidence of glaucoma and the long-term risk of elevated intraocular pressure (IOP) in EX patients is crucial.
Purpose of the Study:
- To determine the incidence of glaucoma in patients with incidental exfoliation (EX) syndrome.
- To assess the long-term course of EX concerning the onset of elevated intraocular pressure (IOP).
Main Methods:
- Retrospective evaluation of 100 patients with incidental EX to determine glaucoma incidence.
- Longitudinal follow-up of 347 patients with normal IOP and EX to track the development of elevated IOP.
Main Results:
- In the first study, 7% of eyes with EX had glaucoma, while 15% had ocular hypertension/glaucoma suspect.
- In the second study, the cumulative probability of developing elevated IOP was 5.3% at 5 years and 15.4% at 10 years for eyes with EX.
- Patients with EX showed a higher incidence of developing elevated IOP than expected for their age group.
Conclusions:
- Exfoliation syndrome is associated with a significant risk of developing glaucoma and elevated intraocular pressure.
- Ophthalmologists should closely monitor patients with exfoliation syndrome for signs of elevated IOP and glaucoma.