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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

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Myocardial CT perfusion imaging for ischemia detection

Patricia Carrascosa1, Carlos Capunay1

  • 1Department of Cardiovascular Imaging, Diagnóstico Maipú, Buenos Aires, Argentina.

Cardiovascular Diagnosis and Therapy
|May 26, 2017
PubMed

Insights

Coronary computed tomography angiography (CCTA) assesses coronary artery anatomy but not ischemia. Myocardial CT perfusion (CTP) using static techniques with SECT or DECT offers a comprehensive evaluation of both anatomy and ischemia.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Coronary computed tomography angiography (CCTA) is vital for assessing coronary artery disease (CAD) in specific patient groups.
  • CCTA limitations include the inability to detect associated ischemia, crucial for managing moderate to severe stenosis.
  • Cardiac CT offers a unique comprehensive evaluation of coronary anatomy and lesion functional significance.

Purpose of the Study:

  • To review the technical parameters of static Myocardial CT Perfusion (CTP).
  • To discuss the clinical evidence for static CTP using both single-energy CT (SECT) and dual-energy CT (DECT).

Main Methods:

  • Review of static and dynamic CTP techniques.
  • Focus on static CTP methods utilizing SECT and DECT.
  • Analysis of technical parameters and clinical evidence for static CTP.

Main Results:

  • Static CTP can be performed using SECT or DECT.
  • CTP provides functional information complementing anatomical data from CCTA.
  • Evidence for static CTP's role in comprehensive cardiac CT evaluation is presented.

Conclusions:

  • Static CTP, using SECT or DECT, enhances cardiac CT's diagnostic capabilities.
  • CTP addresses the limitation of CCTA in assessing ischemia.
  • This review details static CTP's technical aspects and clinical utility.

Keywords:
Computed tomography (CT)dipyridamoledual energy imagingnecrosisperfusion defect

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