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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
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Metastasis of soft tissue sarcomas in lymph node: A cytomorphological study
Jahnavi Gandhi1, Shailee Mehta1, Trupti Patel1
1Department of Pathology, Gujarat Cancer And Research Institute (GCRI), Ahmedabad, Gujarat, India.
Diagnostic Cytopathology
|May 26, 2017
Summary
Fine-needle aspiration cytology (FNAC) is crucial for diagnosing soft-tissue sarcoma (STS) metastasis to lymph nodes. This study confirms FNAC
Area of Science:
- Oncology
- Cytopathology
- Surgical Pathology
Background:
- Soft-tissue sarcoma (STS) exhibits rare lymph node metastasis compared to carcinomas.
- Fine-needle aspiration cytology (FNAC) is essential for diagnosing metastatic tumors in lymph nodes.
Purpose of the Study:
- To evaluate the diagnostic utility of FNAC in identifying soft-tissue sarcoma metastasis to lymph nodes.
Main Methods:
- A 4-year retrospective study involving FNAC of enlarged lymph nodes in STS patients.
- Cytology smears were analyzed with clinical data.
- Histopathology and Immunohistochemistry (IHC) were used for correlation in synchronous cases.
Main Results:
- Out of 326 STS patients, 21 had enlarged lymph nodes, with 19 (5.8%) showing metastasis.
- Rhabdomyosarcoma was the most frequent STS subtype metastasizing to lymph nodes.
- Dermatofibrosarcoma protuberance (DFSP) of the scalp with cervical lymph node metastasis was an unusual case.
Conclusions:
- FNAC is a valuable tool for diagnosing lymph node metastasis in soft-tissue sarcoma cases.
