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Cardiovascular events during carfilzomib therapy for relapsed myeloma: practical management aspects from two case

Andrzej J Jakubowiak1, Jeanne M DeCara2, Khalid Mezzi3

  • 1a Department of Medicine , The University of Chicago Medicine , Chicago , IL , USA.

Hematology (Amsterdam, Netherlands)
|May 27, 2017
PubMed

Insights

Managing cardiovascular events during carfilzomib therapy is crucial for patients with multiple myeloma (MM). Proactive strategies can help prevent and treat these toxicities, allowing continued use of this effective MM treatment.

Area of Science:

  • Cardiology
  • Hematology
  • Oncology

Background:

  • Multiple myeloma (MM) patients face increased cardiovascular risks from disease and treatments.
  • Proteasome inhibitors like carfilzomib are vital MM therapies but can cause cardiovascular toxicities.
  • Mechanisms of carfilzomib-induced cardiovascular events require further understanding.

Keywords:
Carfilzomibcardiovascularmanagementmultiple myelomaproteasome inhibitor

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