Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 1, 2026

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

2.2K

Pediatric Lung Transplantation.

Stuart C Sweet1

  • 1Division of Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri. sweet@kids.wustl.edu.

Respiratory Care
|May 27, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy.

The New England journal of medicine·2026
Same author

Considerations for Endpoints in Lung Transplant Clinical Trials: Perspective on the ISHLT Consensus Statement.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Considerations for Endpoints in Lung Transplant Clinical Trials: An ISHLT Consensus Statement.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

A Perspective on Referral and Selection for Pediatric Lung Transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

International Society for Heart and Lung Transplantation Consensus Statement on the Referral and Selection of Pediatric Lung Transplant Candidates.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

The Affordable Care Act's Call for Nondiscrimination: Addressing the Role of Pulse Oximetry in Racial Disparities.

Annals of the American Thoracic Society·2024

Pediatric lung transplantation offers a viable treatment for children with end-stage lung disease. Innovations in organ availability, patient bridging, and understanding chronic lung allograft dysfunction are key to improving long-term outcomes.

Area of Science:

  • Pediatric Pulmonology
  • Transplantation Medicine
  • Immunology

Background:

  • Pediatric lung transplantation is a critical treatment for end-stage lung disease in children.
  • Over 100 pediatric lung transplants are performed annually, highlighting its significance.
  • Long-term success faces challenges including organ availability and post-transplant complications.

Purpose of the Study:

  • To review current challenges and future opportunities in pediatric lung transplantation.
  • To highlight areas for innovation to improve patient outcomes.
  • To emphasize the need for research into chronic lung allograft dysfunction.

Main Methods:

  • Review of current literature and registry data.
  • Discussion of emerging technologies and strategies.
Keywords:
cystic fibrosislung transplantationorgan donationpulmonary hypertension

More Related Videos

Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

827
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

21.2K

Related Experiment Videos

Last Updated: Mar 1, 2026

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

2.2K
Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

827
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

21.2K
  • Identification of research priorities in pediatric lung transplantation.

    • Main Results:

    • Ex vivo lung perfusion shows promise for expanding the donor organ pool.
    • Extracorporeal support and rehabilitation can bridge critically ill children to transplant.
    • Understanding chronic lung allograft dysfunction mechanisms is crucial for developing new therapies.

    Conclusions:

    • Pediatric lung transplantation is a viable but complex procedure.
    • Advancements in organ preservation, patient support, and understanding of rejection are essential.
    • Further research into chronic lung allograft dysfunction is paramount for long-term success.