Common toxidromes in movement disorder neurology

Area of Science:

• Neurology
• Toxicology
• Internal Medicine

Background:

• Physicians encounter patients with drug or toxin exposure leading to severe adverse effects.
• These exposures can cause significant morbidity and mortality.

Purpose of the Study:

• To summarize key clinical features and management of common movement disorder toxidromes.
• Focus on toxidromes relevant to physicians, particularly neurologists.

Main Methods:

• Systematic literature search of PubMed (1946-2016).
• Focus on papers related to movement toxidromes and their treatments.

Main Results:

• Key features and treatments for 6 common movement disorder toxidromes are presented.
• Detailed discussion on managing high-mortality toxidromes like neuroleptic malignant syndrome and serotonin syndrome.

Conclusions:

• Several toxidromes pose life-threatening emergencies.
• Early recognition of clinical features and prompt treatment are critical for patient outcomes.