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Published on: October 16, 2021
Recurrent mitral paravalvular leak: benefits of leak site repair compared to re-replacement
Jae W Choi1, Ho Y Hwang1, Kyung H Kim1
1Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea.
Background:
Mitral paravalvular leak (PVL) recurrence after surgical correction has not been well demonstrated. The aims of this study were to evaluate the long-term results of surgical mitral PVL correction, including recurrent PVL, and to elucidate the factors - including surgical technique - that affect the risk of recurrent PVL.
Methods:
Eighty-six patients who underwent surgical treatment for mitral PVL were enrolled in this study. Thirty-six patients underwent leak site repair (MVP group), and 50 patients underwent re-replacement (MVR group). Leak site repair was the preferred method and was performed whenever possible. The mean follow-up duration was 58.6±44.1 months (0.1-156.5 months).
Results:
Operative mortality occurred in 7 patients (8.1%). There were no significant differences in operative mortality or postoperative complications between the groups. Overall survival rates at 5 and 10 years were 67.9% and 48.3%, respectively, without intergroup differences. Recurrent PVL without any evidence of infective endocarditis was found in 25 patients (29.1%). Five- and 10-year PVL-free rates were 69.9% and 18.3%, respectively. The mortality rate of reoperation for recurrent PVL was 35.2% (6/17). The risk factors of recurrent PVL were the MVR group (hazard ratio: 2.865, 95% CI: 1.077-7.619) and presence of extensive dehiscence (>25% of annulus: 2.861, 95% CI: 1.163-7.038).
Conclusions:
Recurrent PVL was not infrequent after surgical correction of mitral PVL, and reoperation may be a high-risk procedure. Leak site repair, if it could be performed, would be a good surgical option for mitral PVL because re-replacement was a risk factor for recurrence of PVL.
Insights
Recurrent mitral paravalvular leak (PVL) is common after surgical repair. Leak site repair is a better option than re-replacement to reduce PVL recurrence risk.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Mitral Valve Repair
Background:
- Mitral paravalvular leak (PVL) recurrence after surgical correction is not well-documented.
- Understanding long-term outcomes and recurrence factors is crucial for patient management.
Purpose of the Study:
- To evaluate long-term results of surgical mitral PVL correction.
- To identify factors, including surgical technique, influencing recurrent PVL risk.
Main Methods:
- Retrospective study of 86 patients with mitral PVL.
- Comparison of leak site repair (36 patients) versus valve re-replacement (50 patients).
- Mean follow-up of 58.6 months.
Main Results:
- Recurrent PVL occurred in 29.1% of patients.
- Valve re-replacement (MVR group) and extensive annular dehiscence (>25%) were risk factors for recurrence.
- Reoperation for recurrent PVL had a high mortality rate (35.2%).
Conclusions:
- Recurrent mitral PVL is frequent after surgical correction.
- Leak site repair is a preferred surgical option to minimize recurrence.
- Re-replacement is associated with a higher risk of PVL recurrence.
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