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Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
Genetic polymorphisms of 12 X STR loci in Shaanxi Han population from China
Mao Sun1, YunTao Zhang2, XiaoNan Zhang3
1Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China; Center for DNA Typing, Fourth Military Medical University, Xi'an 710032, China.
Abstract:
Allele frequencies for 12 X STR loci (DXS8378, DXS10159, DXS10162, DXS10164, DXS981, DXS6789, DXS7424, DXS101, DXS7133, GATA165B12, GATA31E08 and DXS7423) were obtained from a sample of 518 unrelated individuals from Shaanxi, China. We observed a total of 108 alleles in the group with the allelic frequency values ranging from less than 0.0014 to 0.6768. Our statistic analysis indicates that the 12 X STR conform to the Hardy-Weinberg's equilibrium. Heterozygosity among the studied 12 X STR loci showed a distribution of 42.33-86.20%. This is first report on allele frequencies of DXS10162 from Han population. The results may provide useful information for forensic sciences and population genetics studies. The present findings indicate that the 12 X STR loci are highly genetically polymorphic in the Han population of Shaanxi.
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