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Kimberly E Liu1, Allison Case2

  • 1Toronto (Ont.).

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC
|May 28, 2017
PubMed
Summary
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Fertility declines naturally with age in both women and men. This clinical guideline reviews ovarian reserve assessment and assisted reproductive technology (ART) for infertility in women of advanced reproductive age.

Area of Science:

  • Reproductive Endocrinology and Infertility
  • Gerontology and Geriatric Medicine
  • Medical Ethics and Health Policy

Context:

  • Increasing awareness of age-related fertility decline in both sexes.
  • Growing utilization of assisted reproductive technologies (ART) for infertility.
  • Need for evidence-based guidelines on managing infertility in advanced reproductive age.

Purpose:

  • To educate the public on age-related fertility decline and ART.
  • To provide management recommendations for infertility in advanced reproductive age.
  • To analyze methods for assessing ovarian aging.

Summary:

  • This clinical guideline reviews ovarian reserve assessment and ART for infertility in women of advanced reproductive age.
  • It synthesizes data from systematic reviews, clinical trials, and observational studies.
Keywords:
Ovarian agingadvanced reproductive ageassisted reproductive technology

Related Experiment Videos

  • Key outcomes include predictive values of ovarian reserve assessments and pregnancy rates from natural and assisted fertility.

    • Impact:

    • Improved patient and healthcare provider knowledge of ovarian aging, age-related fertility decline, and ART.
    • Standardized approach to evaluating and managing infertility in older women.
    • Potential for enhanced reproductive outcomes and informed decision-making.