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Development and validation of CF-Medication Beliefs Questionnaire: A mixed-methods approach
Michelle N Eakin1, Shang-En Chung1, Jessica Hoehn2
1Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, United States.
Summary
A new questionnaire, the Cystic Fibrosis Medication Belief Questionnaire (CF-MBQ), was validated to assess patient beliefs about medications. This tool helps understand medication adherence in cystic fibrosis (CF) patients.
Area of Science:
- Psychology
- Medical Sociology
- Health Psychology
Background:
- Medication beliefs are linked to adherence in various conditions.
- No specific tools existed to measure medication beliefs in cystic fibrosis (CF).
- This study aimed to validate a new questionnaire for CF patients.
Purpose of the Study:
- To develop and validate the Cystic Fibrosis Medication Belief Questionnaire (CF-MBQ).
- To assess medication beliefs based on social cognitive theory.
- To provide a tool for understanding adherence determinants in CF.
Main Methods:
- Developed items based on social cognitive theory domains: motivation, self-efficacy, perceived importance, and decisional balance.
- Refined items through cognitive interviews with 15 adult CF patients.
- Administered an online survey to 128 CF patients and compared results with pharmacy refill data for adherence.
Main Results:
- The CF-MBQ demonstrated strong psychometric properties and good internal consistency across its five subscales.
- Each subscale showed construct validity, correlating with objective medication adherence measures.
- The questionnaire provides a reliable measure of medication beliefs in CF.
Conclusions:
- The validated CF-MBQ is a theoretically-grounded measure for clinical use.
- It can guide interventions aimed at improving medication adherence in CF.
- The questionnaire will enhance research into patient-specific factors influencing adherence.
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