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An Improved Method for Rapid Intubation of the Trachea in Mice

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Tracheobronchomalacia.

Abhishek Biswas¹, Michael A Jantz¹, P S Sriram¹

¹Division of Pulmonary and Critical Care Medicine, University of Florida, Gainesville, FL, United States.

Disease-A-Month : DM

|May 28, 2017

Summary

This summary is machine-generated.

Tracheobronchomalacia, characterized by collapsible airways, is often misdiagnosed. This review covers its causes, symptoms, diagnosis, and varied treatments, including conservative and surgical options.

Keywords:

Central airway obstruction Endobronchial ultrasound Excessive dynamic airway collapse Tracheobronchial stent Tracheobronchomalacia

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Area of Science:

Pulmonology
Respiratory Medicine
Medical Diagnostics

Background:

Tracheobronchomalacia involves excessive compliance and collapse of central airways, leading to various respiratory symptoms.
It is frequently misdiagnosed as asthma, bronchitis, or chronic cough due to non-specific clinical presentations.
While often a coexisting condition, it can independently cause significant symptoms.

Purpose of the Study:

To elucidate the pathophysiology of tracheobronchomalacia.
To identify common symptoms and underlying causes.
To outline diagnostic approaches and cause-specific therapeutic interventions.

Main Methods:

Review of existing literature on tracheobronchomalacia.
Discussion of diagnostic modalities including imaging, lung function testing, and flexible bronchoscopy.
Analysis of treatment strategies ranging from conservative management to surgical interventions.

Main Results:

Tracheobronchomalacia presents with diverse symptoms and can be mistaken for other pulmonary conditions.
Diagnosis relies on a combination of clinical evaluation, imaging, pulmonary function tests, and bronchoscopy.
Treatment is tailored to the underlying cause, with non-invasive ventilation being common, alongside potential surgery or stenting.

Conclusions:

Accurate diagnosis of tracheobronchomalacia requires a comprehensive approach, differentiating it from other airway diseases.
Understanding the pathophysiology is key to effective management.
Therapeutic options are varied, emphasizing personalized treatment based on etiology and severity.