Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

1.9K
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
1.9K
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

1.0K
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
1.0K
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

1.0K
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.0K
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.3K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.3K
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

1.0K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.0K
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.6K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety Assessment of Perioperative Pain Medications for Children: Variation in Opioid Prescribing at Discharge.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches·2026
Same author

Postoperative Fever as a Predictor of Surgical Site Infection in Pediatric Complicated Appendicitis.

Journal of the American College of Surgeons·2026
Same author

Handing off hope: transition of care in pediatric surgery.

Surgical endoscopy·2026
Same author

Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study.

Journal of pediatric surgery·2025
Same author

SAGES-AHPBA 2025 guideline for the surgical management of bile duct injury following cholecystectomy.

Surgical endoscopy·2025
Same author

SAGES 2025 guidelines for fluorescence image-guided gastrointestinal surgery using indocyanine green.

Surgical endoscopy·2025
Same journal

The EXTra-uterine Environment for Neonatal Development (EXTEND) - future treatment for prematurity and potentially other congenital disease.

Seminars in pediatric surgery·2026
Same journal

Appendicitis as a model for pediatric surgical quality improvement and standardization.

Seminars in pediatric surgery·2026
Same journal

From FOB to PICU: military trauma systems that changed pediatrics.

Seminars in pediatric surgery·2026
Same journal

Long-term follow-up after surgery for congenital anomalies: A time to complication analysis.

Seminars in pediatric surgery·2026
Same journal

Radio-surgical decision-making in hepatoblastoma in the post-PHITT era: SIOPEL consensus recommendations.

Seminars in pediatric surgery·2026
Same journal

Seminars in pediatric sugery pediatric metabolic and bariatric surgery.

Seminars in pediatric surgery·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Surgical Models of Gastroesophageal Reflux with Mice
05:19

Surgical Models of Gastroesophageal Reflux with Mice

Published on: August 25, 2015

10.8K

Gastroesophageal reflux.

Bethany J Slater1, Steven S Rothenberg1

  • 1Pediatric Surgery, Rocky Mountain Hospital for Children, Denver, Colorado.

Seminars in Pediatric Surgery
|May 29, 2017
PubMed
Summary
This summary is machine-generated.

Gastroesophageal reflux disease (GERD) in children often requires surgery when medical treatments fail. Laparoscopic Nissen fundoplication is the standard surgical approach for pediatric GERD, focusing on specific technical steps for optimal outcomes.

Keywords:
ChildrenFundoplicationGERDGastroesophageal refluxMinimally invasiveNissenPediatricsRefluxWrap

More Related Videos

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

3.4K
Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

3.0K

Related Experiment Videos

Last Updated: Mar 1, 2026

Surgical Models of Gastroesophageal Reflux with Mice
05:19

Surgical Models of Gastroesophageal Reflux with Mice

Published on: August 25, 2015

10.8K
Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

3.4K
Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

3.0K

Area of Science:

  • Pediatric Surgery
  • Gastroenterology

Background:

  • Gastroesophageal reflux disease (GERD) affects 7-20% of children, presenting with symptoms like regurgitation, feeding irritability, and respiratory issues.
  • Medical management, including dietary changes and medications, is the initial treatment approach for pediatric GERD.

Purpose of the Study:

  • To outline the indications and standard surgical technique for managing pediatric GERD.
  • To detail the key technical aspects of laparoscopic Nissen fundoplication in children.

Main Methods:

  • Review of indications for surgical intervention in pediatric GERD.
  • Description of the standard laparoscopic Nissen fundoplication procedure for children.

Main Results:

  • Surgical intervention is indicated for pediatric GERD when medical therapy fails, leading to poor weight gain, failure to thrive, persistent respiratory symptoms, or complications like esophagitis.
  • Laparoscopic Nissen fundoplication is the established surgical standard of care.

Conclusions:

  • Laparoscopic Nissen fundoplication is a safe and effective surgical treatment for pediatric GERD unresponsive to medical management.
  • Precise technical execution, including adequate intra-abdominal esophagus creation, crural repair, and a floppy 360° wrap, is crucial for successful outcomes.