[PARATHYROID AUTOTRANSPLANTATION IN ADULTS AND CHILDREN].

Area of Science:

• Endocrine Surgery
• Transplantation Medicine
• Surgical Pathology

Background:

• Parathyroid autotransplantation is indicated for hypoparathyroidism following parathyroid hyperplasia or inadvertent gland damage during neck surgery.
• Cryopreservation offers delayed transplantation for parathyroid glands, effective for up to two years.
• Permanent hypoparathyroidism after thyroidectomy, neck surgery, or in cases of hyperplasia necessitates autotransplantation.

Purpose of the Study:

• To review the indications and methods for parathyroid autotransplantation in pediatric and adult patients.
• To emphasize immediate and cryopreserved delayed autotransplantation techniques.
• To highlight the importance of specialized endocrine surgical centers for successful outcomes.

Main Methods:

• Review of parathyroid autotransplantation techniques, including immediate and cryopreserved delayed methods.
• Analysis of indications for autotransplantation, such as parathyroid hyperplasia and surgical damage.
• Discussion of factors influencing autotransplantation success rates.

Main Results:

• Autotransplantation, particularly during thyroidectomy, can significantly reduce or eliminate postoperative hypoparathyroidism.
• Success rates are variable, depending on timing, underlying disease, and tissue storage duration.
• Cryopreserved parathyroid glands can be effectively transplanted up to two years post-storage.

Conclusions:

• Parathyroid autotransplantation is a crucial procedure for managing hypoparathyroidism in specific surgical contexts.
• Experienced endocrine surgical centers are essential for optimal patient outcomes.
• While variable, autotransplantation offers a viable solution for preventing permanent hypoparathyroidism.