Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Radiation Therapy Infrastructure, Social Vulnerability, and Insurance Architecture Predict Timely Postoperative Radiation Therapy After Brain Tumor Craniotomy.

Advances in radiation oncology·2026

Same author

Functional and Cosmetic Outcomes of Pterional Craniotomy and Its Modifications: A Scoping Review.

Cureus·2026

Same author

Incidence and Prognosis of Delayed Facial Nerve Palsy After Vestibular Schwannoma Resection: Systematic Review and Meta-analysis.

Journal of neurological surgery. Part B, Skull base·2026

Same author

A filum terminale arteriovenous fistula fed by the left L1 artery of adamkiewicz: a case report and updated systematic review of 71 cases.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2025

Same author

Corrigendum: High-dose fluorescein reveals unusual confocal endomicroscope imaging of low-grade glioma.

Frontiers in neurology·2025

Same author

The safety and feasibility of anticoagulant resumption following middle meningeal artery embolization in patients with subacute subdural hematomas.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2025

Search research articles

Related Experiment Video

Updated: Mar 1, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

Thalamic cavernous malformations.

Christina E Sarris¹, Gursant S Atwal¹, Peter Nakaji¹

¹Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.

Handbook of Clinical Neurology

|May 30, 2017

Summary

Cavernous malformations in the thalamus are complex due to eloquent tissue and deep location. Surgical decisions and approaches for thalamic cavernous malformations depend on lesion specifics and patient factors.

Keywords:

cavernous malformation image guidance natural history safe entry zones surgery thalamus

More Related Videos

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Related Experiment Videos

Last Updated: Mar 1, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Area of Science:

Neurosurgery
Neurology
Vascular Malformations

Background:

Cavernous malformations (CMs) in the thalamus present unique surgical challenges owing to the critical function of thalamic tissue and the lesions' deep-seated positions.
The management of thalamic CMs requires careful consideration of lesion location, patient symptomatology, and medical history.

Purpose of the Study:

To outline the complexities and surgical considerations for treating cavernous malformations within the thalamus.
To detail the various surgical approaches required for accessing different regions of the thalamus for CM resection.

Main Methods:

Review of surgical approaches for thalamic cavernous malformations.
Categorization of surgical techniques based on the specific thalamic location of the lesion.

Main Results:

Specific surgical approaches are tailored to distinct thalamic locations: orbitozygomatic for anteroinferior, interhemispheric transcallosal variants for medial and lateral thalamus, parieto-occipital transventricular for lateral posteroinferior, and suboccipital supracerebellar infratentorial/transtentorial for medial posteroinferior CMs.
Successful and safe resection of thalamic CMs is achievable with meticulous attention to safe entry corridors and the utilization of image guidance.

Conclusions:

Surgical intervention for thalamic cavernous malformations necessitates a tailored approach based on precise anatomical localization.
The selection of an appropriate surgical strategy, guided by anatomical knowledge and advanced imaging, is crucial for achieving safe and effective lesion removal.