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Published on: September 24, 2021
Case of pacemaker pocket infection caused by Finegoldia magna
Seyed Hamed Hosseini Dehkordi1, Georgina Osorio2
1Department of Medicine, Icahn School of Medicine at Mount Sinai St. Luke's and Mount Sinai West Hospital Center, New York, NY, United States.
Abstract:
Finegoldia magna (formerly called Peptostreptococcus magnus) is a Gram-positive anaerobic coccus which is increasingly recognized as an opportunistic pathogen. We present a case of F. magna associated non-valvular cardiovascular device-related infection in an 83 year-old male who received a permanent pacemaker for sick sinus syndrome seven weeks prior to his presentation. Five weeks after the implantation, the pacemaker and leads were explanted because of clinical evidence of pacemaker pocket infection. He was initially treated with sulfamethoxazole-trimethoprim based on the Gram stain results from the removed pacemaker. However, two weeks later, he was readmitted with sepsis and was successfully treated with ampicillin-sulbactam. Culture results from the pacemaker and pocket as well as blood cultures grew F. magna. Clinicians should be aware of the possibility of F. magna infection when initial gram stain results show "gram positive cocci".
Insights
Finegoldia magna, a Gram-positive anaerobic coccus, can cause opportunistic infections. This case highlights F. magna infection in a patient with a permanent pacemaker, emphasizing the need for clinical awareness.
Area of Science:
- Microbiology
- Infectious Diseases
- Cardiology
Background:
- Finegoldia magna (formerly Peptostreptococcus magnus) is an anaerobic Gram-positive coccus increasingly recognized as an opportunistic pathogen.
- Cardiovascular device-related infections pose significant clinical challenges.
Observation:
- An 83-year-old male developed a pacemaker pocket infection seven weeks after permanent pacemaker implantation for sick sinus syndrome.
- Initial treatment with sulfamethoxazole-trimethoprim was unsuccessful, leading to readmission with sepsis.
Findings:
- Infection was confirmed to be caused by Finegoldia magna through cultures of the explanted pacemaker, pocket tissue, and blood.
- The patient was successfully treated with ampicillin-sulbactam for sepsis.
Implications:
- Clinicians should consider F. magna in the differential diagnosis of Gram-positive cocci infections, particularly in patients with cardiovascular devices.
- Prompt and accurate identification and appropriate antibiotic selection are crucial for managing F. magna infections.
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