Charge-tagged ligands: useful tools for immobilising complexes and detecting reaction species during catalysis
Jones Limberger1, Bárbara C Leal1, Adriano L Monteiro1
1Laboratory of Molecular Catalysis , Institute of Chemistry - UFRGS , Av. Bento Gonçalves 9500, 91501-970, CP 15003 , Porto Alegre , RS , Brazil .
Abstract:
In recent years, charge-tagged ligands (CTLs) have become valuable tools in organometallic catalysis. Insertion of an ionic side chain into the molecular skeleton of a known ligand has become a useful protocol for anchoring ligands, and consequently catalysts, in polar and ionic liquid phases. In addition, the insertion of a cationic moiety into a ligand is a powerful tool that can be used to detect reaction intermediates in organometallic catalysis through electrospray ionisation mass spectrometry (ESI-MS) experiments. The insertion of an ionic tag ensures the charge in the intermediates independently of the ESI-MS. For this reason, these ligands have been used as ionic probes in mechanistic studies for several catalytic reactions. Here, we summarise selected examples on the use of CTLs as immobilising agents in organometallic catalysis and as probes for studying mechanisms through ESI-MS.
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