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Cystosarcoma phyllodes--Asian variations.

C L Chua1, A Thomas, B K Ng

  • 1Department of Surgery, Alexandra Hospital, Singapore.

The Australian and New Zealand Journal of Surgery
|April 1, 1988
PubMed
Summary
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Phyllodes tumors are more common in Asian women, who are typically younger than Western patients. This study reviewed 106 Asian patients, noting variations in phyllodes tumor incidence and patient demographics compared to Western populations.

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Phyllodes tumors are rare breast neoplasms with variable clinical behavior.
  • Previous studies suggest potential racial predilections for phyllodes tumors.
  • Understanding demographic variations is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To review the clinical characteristics of phyllodes tumors in an Asian population.
  • To compare incidence, patient demographics, and tumor behavior with Western cohorts.
  • To explore potential associations with other breast diseases.

Main Methods:

  • Retrospective review of 106 female patients diagnosed with phyllodes tumors.
  • Analysis of tumor incidence, patient age, and clinical presentation.

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  • Comparison of findings with published data from Western populations.
  • Main Results:

    • Phyllodes tumors constituted 3.83% of surgically removed breast tumors in this Asian cohort.
    • Asian patients were significantly younger (25-30 years) than Western counterparts (40s).
    • A lower incidence of malignant (3%) and borderline (5.7%) tumors was observed compared to Western series.

    Conclusions:

    • Non-Caucasian populations may have a higher predisposition to phyllodes tumors.
    • Younger age at presentation in Asian patients can lead to clinical misdiagnosis as fibroadenoma.
    • The study highlights the need for considering phyllodes tumors in younger women, especially in Asian populations.