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Related Concept Videos

Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

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The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
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Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

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Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
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Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

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Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Hypertension I: Introduction01:28

Hypertension I: Introduction

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Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
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Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

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Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
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Updated: Mar 1, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
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Hypertensive Disorders in Pregnancy Current Practice Review.

Kim Turner1, Afshan B Hameed2

  • 1University of Southern California - Global Health Los Angeles, California, CA 90012. United States.

Current Hypertension Reviews
|May 31, 2017
PubMed
Summary

Hypertensive disorders complicate 3-5% of pregnancies, causing significant maternal mortality. Developing global guidelines for detection, prophylaxis, and management of these conditions is crucial.

Keywords:
Global burden of diseasebreast feeding and anti-hypertensivescare of women in the postnatal periodcomplicationsdiagnosismanagementmonitoringpathophysiologyreducing the risk of hypertensive disorders in pregnancyrisk factors

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Last Updated: Mar 1, 2026

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Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine

Background:

  • Hypertensive disorders, including preeclampsia, eclampsia, gestational hypertension, and superimposed chronic hypertension, affect 3-5% of pregnancies.
  • These conditions are a major cause of maternal mortality and morbidity.
  • Preeclampsia is a multi-system disorder characterized by new-onset hypertension and proteinuria after 20 weeks of gestation.

Purpose of the Study:

  • To highlight the need for evidence-based clinical guidelines for the detection, prophylaxis, and management of hypertensive disorders in pregnancy worldwide.

Main Methods:

  • This study is a review of the current understanding and challenges in managing hypertensive disorders during pregnancy.
  • It emphasizes the diagnostic criteria for proteinuria, such as 300 mg/24 hours or a protein:creatinine ratio of 0.3 mg/dL.
  • The complex pathophysiology involving abnormal placentation and maternal response is discussed.

Main Results:

  • The pathophysiology of hypertensive disorders is complex, with no single diagnostic test or cure.
  • Access to antenatal care in high-income countries is linked to lower maternal mortality rates from these conditions.

Conclusions:

  • There is an ongoing need for the development and implementation of globally consistent, evidence-based clinical guidelines.
  • These guidelines should address the detection, prophylaxis, and management of hypertensive disorders in pregnancy to improve maternal outcomes.