Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lateralization01:28

Lateralization

1.1K
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
1.1K
Cerebral Hemispheres01:05

Cerebral Hemispheres

2.7K
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
2.7K
Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

4.0K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
4.0K
Language and Cognition01:27

Language and Cognition

891
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
891
Somatosensation01:33

Somatosensation

44.0K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
44.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Machine Learning Approach to Prioritize Place-Based Prevention to Address Cardiovascular Disease Burden in New York City.

American journal of preventive medicine·2026
Same author

Critical feedback impacts creative ideation and brain oscillations.

Neuropsychologia·2025
Same author

Semantic processing of regional varieties in native Spanish listeners: the role of accent familiarity.

Brain and language·2025
Same author

CAP: The creativity assessment platform for online testing and automated scoring.

Behavior research methods·2025
Same author

Neural mechanisms of face cue predictability and the integration of facial and acoustic cues in native- and nonnative-accented words.

Brain and language·2025
Same author

Creativity supports learning through associative thinking.

NPJ science of learning·2025

Related Experiment Video

Updated: Mar 1, 2026

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

1.2K

How right is left? Handedness modulates neural responses during morphosyntactic processing.

Sarah Grey1, Darren Tanner2, Janet G van Hell3

  • 1Department of Modern Languages and Literatures, Fordham University, Faber Hall 556, Bronx, NY 10458, USA.

Brain Research
|May 31, 2017
PubMed
Summary

Handedness influences language processing. Left-handers and right-handers with left-handed relatives show varied neural responses (N400-P600), unlike right-handers without left-handed relatives (P600 only). This highlights ignored variability in neurocognitive language models.

Keywords:
Event-related potentialsHandednessIndividual differencesSyntax

More Related Videos

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

983
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

7.3K

Related Experiment Videos

Last Updated: Mar 1, 2026

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

1.2K
A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

983
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

7.3K

Area of Science:

  • Neuroscience
  • Psycholinguistics
  • Cognitive Science

Background:

  • Neurocognitive models of language often assume uniform neural mechanisms for comprehension.
  • Individual differences, like handedness, significantly impact neural mechanisms in language processing.
  • Left-handers and familial sinistrals (right-handers with left-handed relatives) may process language differently than right-handers without left-handed relatives.

Purpose of the Study:

  • To investigate the effect of handedness profiles on morphosyntactic language processing.
  • To compare neural responses during language comprehension across left-handers, familial sinistral right-handers, and non-familial sinistral right-handers.
  • To examine variability in neural responses within these handedness groups.

Main Methods:

  • Utilized event-related potentials (ERPs) to measure brain activity.
  • Tested three groups: left-handers (LH), right-handers with familial sinistrality (RH FS+), and right-handers without familial sinistrality (RH FS-).
  • Analyzed morphosyntactic processing by observing P600 and N400 components.

Main Results:

  • Right-handers without familial sinistrality (RH FS-) predominantly exhibited P600 responses.
  • Left-handers (LH) and right-handers with familial sinistrality (RH FS+) displayed biphasic N400-P600 patterns.
  • LH and RH FS+ groups showed significant individual variability, with roughly half being N400-dominant and half P600-dominant, unlike the low variability in RH FS-.

Conclusions:

  • Familial sinistrality and left-handedness are associated with increased reliance on lexical/semantic mechanisms (N400) during morphosyntactic processing.
  • Existing neurocognitive language models may be limited by their focus on right-handers without considering familial sinistrality.
  • There is systematic, often overlooked, variability in language processing outcomes within neurologically healthy populations based on handedness profiles.