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Published on: February 4, 2021
Streptococcus bovis prosthetic valve endocarditis associated with silent colonic carcinoma
Fatehi E Elzein1, M Yasin Akhtar2, Hatim Khairallah2
1Department of Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Insights
Streptococcus bovis endocarditis in a patient with a bioprosthetic mitral valve was successfully treated with ceftriaxone. The case highlights the crucial link between S. bovis and colon cancer, emphasizing the need for physician awareness for early diagnosis.
Area of Science:
- Infectious Diseases
- Cardiology
- Gastroenterology
Background:
- The association between Streptococcus bovis endocarditis and colonic neoplasms is a recognized phenomenon.
- Despite established knowledge, a significant gap in physician awareness persists regarding this association.
Observation:
- A 75-year-old female presented with fever and was diagnosed with Streptococcus bovis endocarditis on a bioprosthetic mitral valve.
- Blood cultures cleared with ceftriaxone, but a screening colonoscopy revealed an invasive colonic adenocarcinoma, despite the absence of gastrointestinal symptoms.
Findings:
- The case demonstrates a successful treatment of S. bovis endocarditis with ceftriaxone.
- The concurrent diagnosis of colon cancer underscores the critical need for vigilance in patients with S. bovis endocarditis.
Implications:
- Increased physician awareness of the S. bovis-colon cancer link can lead to earlier diagnosis and improved patient outcomes.
- This case report emphasizes the importance of screening for colonic pathology in patients with S. bovis endocarditis, particularly in regions with lower reported incidence.
Abstract:
A 75-year-old woman was admitted to our hospital with a 3-month history of fever. Of note, she had a bioprosthetic mitral valve replacement 1 year prior to admission. Streptococcus bovis was isolated from three sets of blood cultures. An echocardiogram showed a flickering mass attached to the bioprosthesis. Her blood culture became sterile by the fourth day of ceftriaxone therapy. In spite of the absence of gastrointestinal symptoms, screening colonoscopy revealed an invasive colonic adenocarcinoma. The association linking S. bovis endocarditis and colonic tumours is well recognised. However, despite early reports of this association by Klein et al in 1979, a large number of practising physicians remain unaware of this phenomenon. This lack of awareness results in lost opportunities for early diagnosis and, consequently, improved outcome in such patients. Our report emphasises this association in an area with a low incidence of S. bovis endocarditis.
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