The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

T cell signaling abnormalities in systemic lupus erythematosus are associated with increased mutations/polymorphisms and splice variants of T cell receptor zeta chain messenger RNA.

Arthritis and rheumatism·2001

Protein kinase A RI beta subunit deficiency in lupus T lymphocytes: bypassing a block in RI beta translation reconstitutes protein kinase A activity and augments IL-2 production.

Journal of immunology (Baltimore, Md. : 1950)·2001

Fc epsilon receptor type I gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus.

Arthritis and rheumatism·2001

Polymorphisms/mutations of TCR-zeta-chain promoter and 3' untranslated region and selective expression of TCR zeta-chain with an alternatively spliced 3' untranslated region in patients with systemic lupus erythematosus.

Journal of autoimmunity·2001

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950)·2001

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells.

Proceedings of the National Academy of Sciences of the United States of America·2001

The origin and significance of anti-DNA antibodies.

Immunology today·2014

Mutations of class II MHC molecules.

Immunology today·2014

Antigen processing at the molecular level.

Immunology today·2014

Phenotypically and functionally distinct T-cell subsets in anti-tumor responses.

Immunology today·2014

Are MHC class II-restricted cytotoxic T lymphocytes important?

Immunology today·2014

Complement and the regulation of humoral immune responses.

Immunology today·2014

Peri-interventional neutrophil extracellular traps and immune surveillance in hepatocellular carcinoma: mechanisms, biomarkers, and recurrence after liver resection or thermal ablation.

Frontiers in oncology·2026

Enhancing intravesical bladder cancer therapy: from mucoadhesive to targeted drug delivery strategies.

Frontiers in medicine·2026

Gefitinib-based therapy in refractory hepatocellular carcinoma with EGFR overexpression: a spatial profiling-guided case report.

Frontiers in immunology·2026

Lysosome-Bursting Calcium Carbonate Nanoparticles Amplify Immunogenic Cell Death via Synergistic Phototherapy and Calcium Overload for Immune Checkpoint Blockade.

Research (Washington, D.C.)·2026

Bio-based nanophotothermal systems as smart drug delivery platforms for multimodal synergistic cancer therapy-a review.

Frontiers in medical technology·2026

Stable disease after multimodal treatment of SMARCA4-deficient undifferentiated tumor concurrently involving the stomach and mediastinum: a case report.

Frontiers in oncology·2026

Related Experiment Videos

The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

Related Concept Videos

T cell signaling abnormalities in systemic lupus erythematosus are associated with increased mutations/polymorphisms and splice variants of T cell receptor zeta chain messenger RNA.

Protein kinase A RI beta subunit deficiency in lupus T lymphocytes: bypassing a block in RI beta translation reconstitutes protein kinase A activity and augments IL-2 production.

Fc epsilon receptor type I gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus.

Polymorphisms/mutations of TCR-zeta-chain promoter and 3' untranslated region and selective expression of TCR zeta-chain with an alternatively spliced 3' untranslated region in patients with systemic lupus erythematosus.

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus.

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells.

The origin and significance of anti-DNA antibodies.

Mutations of class II MHC molecules.

Antigen processing at the molecular level.

Phenotypically and functionally distinct T-cell subsets in anti-tumor responses.

Are MHC class II-restricted cytotoxic T lymphocytes important?

Complement and the regulation of humoral immune responses.

Peri-interventional neutrophil extracellular traps and immune surveillance in hepatocellular carcinoma: mechanisms, biomarkers, and recurrence after liver resection or thermal ablation.

Enhancing intravesical bladder cancer therapy: from mucoadhesive to targeted drug delivery strategies.

Gefitinib-based therapy in refractory hepatocellular carcinoma with EGFR overexpression: a spatial profiling-guided case report.

Lysosome-Bursting Calcium Carbonate Nanoparticles Amplify Immunogenic Cell Death via Synergistic Phototherapy and Calcium Overload for Immune Checkpoint Blockade.

Bio-based nanophotothermal systems as smart drug delivery platforms for multimodal synergistic cancer therapy-a review.

Stable disease after multimodal treatment of SMARCA4-deficient undifferentiated tumor concurrently involving the stomach and mediastinum: a case report.

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The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

Related Concept Videos

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