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Leukopenia Associated with Risperidone Treatment.

Matthew Morrison1, Autumn Schultz1, Deborah L Sanchez2

  • 1University of South Florida Department of Psychiatry and Behavioral Neurosciences, Tampa, FL,United States.

Current Drug Safety
|June 1, 2017
PubMed
Summary
This summary is machine-generated.

Risperidone, an antipsychotic, can rarely cause leukopenia (low white blood cell count). This case study examines a patient who developed this side effect and reviews associated risk factors.

Keywords:
Atypical antipsychoticleukopenianeutrophil countrisperidoneside effectswhite blood cell count.

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Area of Science:

  • Pharmacology
  • Hematology
  • Clinical Medicine

Background:

  • Risperidone is an atypical antipsychotic used for schizophrenia.
  • Common side effects include weight gain, anxiety, extra-pyramidal symptoms, and elevated prolactin.
  • Leukopenia is a rare but serious adverse effect associated with risperidone use.

Purpose of the Study:

  • To present a case of a 66-year-old male who developed leukopenia after starting risperidone for delirium-induced agitation.
  • To review previously reported cases of risperidone-associated leukopenia.
  • To explore potential risk factors for developing leukopenia in patients treated with risperidone.

Main Methods:

  • Case report presentation.
  • Literature review of existing case studies on risperidone-induced leukopenia.
  • Analysis of potential risk factors based on reported cases.

Main Results:

  • A 66-year-old male patient developed leukopenia following risperidone initiation.
  • Review of literature identified other instances of leukopenia linked to risperidone.
  • Identified potential risk factors contributing to the development of leukopenia.

Conclusions:

  • Risperidone can induce leukopenia, a rare adverse effect.
  • Awareness of this potential side effect is crucial for clinicians.
  • Further investigation into risk factors may aid in patient management and prevention.