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Related Experiment Video

Updated: Mar 1, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

557

Bone Margin Analysis for Benign Odontogenic Tumors.

Eric Ringer1, Antonia Kolokythas2

  • 1Department of Oral and Maxillofacial Surgery, University of Rochester-Eastman Institute for Oral Health, 601 Elmwood ave, Box 705, Rochester, NY 14642, USA.

Oral and Maxillofacial Surgery Clinics of North America
|June 1, 2017
PubMed
Summary

Information on bone invasion by odontogenic tumors is limited, hindering evidence-based treatment guidelines. Further multicenter studies are needed to establish clear resection margins for these rare tumors.

Keywords:
AmeloblastomaMandibleMaxillaOdontogenic tumorSurgical margin

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Oncology
  • Pathology

Background:

  • Odontogenic tumors are rare neoplasms with variable treatment approaches.
  • Limited data exists regarding the precise tumor-bone interface and bone invasion extent for most odontogenic tumors, except potentially ameloblastoma.
  • Current treatment practices lack robust scientific evidence, necessitating further research.

Purpose of the Study:

  • To highlight the lack of information on bone invasion by common odontogenic tumors.
  • To emphasize the need for evidence-based guidelines for managing these rare conditions.
  • To propose a basis for determining adequate bone resection margins in the absence of comprehensive data.

Main Methods:

  • Review of existing literature on odontogenic tumors and bone invasion.
  • Analysis of the current understanding of tumor-bone interface in rare oral neoplasms.
  • Discussion of the limitations in current data for establishing treatment protocols.

Main Results:

  • Information on the exact tumor-bone interface and bone invasion by most odontogenic tumors is currently lacking.
  • Scientific evidence supporting commonly accepted treatment practices for these tumors is limited.
  • Prospective multicenter studies are required to develop evidence-based guidelines.

Conclusions:

  • The precise extent of bone invasion by odontogenic tumors remains poorly understood, impacting treatment strategies.
  • There is a critical need for high-quality, multicenter research to establish definitive guidelines for odontogenic tumor management.
  • Until such studies are available, treatment decisions, including bone resection margins, will rely on limited existing data.