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The Relationship between Brachial-Ankle Pulse Wave Velocity and Depressive Symptoms among Patients with Coronary

I-Mei Lin1, Hsueh-Chen Lu1, Chih-Sheng Chu2,3

  • 1Department of Psychology, College of Humanities and Social Sciences, Kaohsiung Medical University.

Acta Cardiologica Sinica
|June 1, 2017
PubMed

Insights

Somatic symptoms of depression, like fatigue, are linked to arterial stiffness in coronary artery disease (CAD) patients. This finding highlights the connection between physical manifestations of depression and cardiovascular health.

Area of Science:

  • Cardiology
  • Psychiatry
  • Vascular Medicine

Background:

  • Arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV), is a key indicator in coronary artery disease (CAD).
  • Depression is associated with increased adverse cardiac events and mortality in CAD patients.
  • Understanding the interplay between arterial stiffness and depression is crucial for managing CAD.

Purpose of the Study:

  • To investigate the relationship between arterial stiffness and depressive symptoms in patients with coronary artery disease (CAD).

Main Methods:

  • Eighty-six CAD patients were assessed for demographic characteristics and depressive symptoms using the Beck Depression Inventory II.
  • Resting brachial-ankle pulse wave velocity (baPWV) was measured noninvasively.
  • Participants were categorized into mild and severe arteriosclerosis groups based on baPWV values.

Main Results:

  • Severe arteriosclerosis group showed higher somatic depression symptoms (concentration difficulty, appetite changes, fatigue) compared to the mild group, even after adjusting for age, beta-blocker use, and left ventricular ejection fraction.
  • Multiple regression analysis revealed that baPWV was significantly associated with somatic depression symptoms, independent of CAD risk factors.
  • No significant association was found between baPWV and cognitive depression symptoms or the total depression score.

Conclusions:

  • Somatic symptoms of depression are significantly related to arterial stiffness in patients with coronary artery disease (CAD).
  • This suggests a specific link between the physical manifestations of depression and vascular health in this population.
Abstract

Keywords:
Arterial stiffnessCADDepression

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