Related Experiment Video
Updated: Mar 1, 2026

07:29
Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound
Published on: October 4, 2021
2.9K
[Ultra-widefield angiography for retinal vein occlusion : How large is large enough?]
1Augenklinik, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland. marcus.storch@med.uni-goettingen.de.
Summary
A 102° fundus angiography image is sufficient to detect clinically relevant ischemic areas in retinal vein occlusion. This imaging method with the Spectralis camera is fast, exact, and may replace older techniques for assessing ischemia.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Full fundus angiography (FAG) aids in diagnosing retinal vein occlusion (RVO).
- The necessary retinal visualization extent for assessing neovascularization risk in RVO remains unclear.
- The 102° Spectralis camera's utility for imaging beyond central views was investigated.
Purpose of the Study:
- To determine if imaging beyond the central 102° is necessary for evaluating neovascularization risk in RVO.
- To assess the sufficiency of a 102° fovea-centered FAG image for evaluating ischemic areas in RVO.
Main Methods:
- Retrospective analysis of 80 eyes from 80 patients with RVO.
- Utilized the ultra-widefield 102° Spectralis camera to analyze central and peripheral ischemia.
- Quantified ischemic areas (IA) using standard viewer software and pixel measurements.
Main Results:
- Ischemic areas were detected in 49 of 51 RVO eyes with IA.
- The average IA constituted 23.5% of the total image area and 53.7% of disc areas in affected eyes.
- Fovea-centered FAG images successfully identified relevant ischemic extents.
Conclusions:
- A 102° fovea-centered FAG image is adequate for determining clinically relevant ischemic areas in RVO.
- Current recommendations and imaging methods for RVO may require reevaluation.
- The 102° Spectralis camera offers a suitable, efficient, and precise method for documenting ischemia extent.

