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Endothelial Cell Tube Formation Assay for the In Vitro Study of Angiogenesis
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Endoglin moves and shapes endothelial cells.

Victoria L Bautch1

  • 1Department of Biology and McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

Nature Cell Biology
|June 1, 2017
PubMed
Summary

Improper blood vessel development, causing arteriovenous shunts, is linked to defects in endoglin, a TGFβ/BMP co-receptor. This receptor is crucial for guiding endothelial cell responses to molecular signals and blood flow.

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