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Published on: May 21, 2019
Personalized hemodynamic management
Bernd Saugel1, Jean-Louis Vincent, Julia Y Wagner
1aDepartment of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany bDepartment of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
Insights
Personalized hemodynamic management optimizes patient care by tailoring blood pressure targets to individual needs, moving beyond fixed values. This approach enhances cardiovascular dynamics for critically ill patients in the operating room and ICU.
Area of Science:
- Critical Care Medicine
- Cardiovascular Physiology
- Anesthesiology
Background:
- Traditional hemodynamic management often relies on population-based normal values.
- Individual variability in hemodynamic parameters necessitates a personalized approach.
- Critically ill patients require tailored strategies for optimal cardiovascular support.
Purpose of the Study:
- To outline personalized hemodynamic management strategies for critically ill patients.
- To highlight the shift from fixed to individualized hemodynamic targets.
- To discuss the application in perioperative and intensive care unit settings.
Main Methods:
- Utilizing patient-specific biometric data and clinical context for target setting.
- Employing functional assessment of fluid responsiveness to optimize cardiac output.
- Leveraging noninvasive technologies for preoperative hemodynamic profiling.
- Implementing adaptive multiparametric monitoring in the ICU.
Main Results:
- Personalized blood pressure management considers individual autoregulation and hypertension history.
- Individualized strategies optimize cardiac output and oxygen delivery.
- Noninvasive techniques allow for targeting preoperatively determined personal hemodynamic values.
- Adaptive monitoring facilitates personalized hemodynamic management in the ICU.
Conclusions:
- Personalized hemodynamic management sets targets based on individual normal values, adjusted for biometrics and clinical status.
- This tailored approach optimizes cardiovascular dynamics according to each patient's unique profile.
- Personalized strategies improve hemodynamic management in critical care settings.
Purpose Of Review:
To describe personalized hemodynamic management of critically ill patients in the operating room and the ICU.
Recent Findings:
Several recent clinical studies have investigated different strategies for optimizing blood pressure (BP) and flow in the operating room and in the ICU. In the past, (early) goal-directed hemodynamic treatment strategies often used predefined fixed population-based 'normal' values as hemodynamic targets. Most hemodynamic variables, however, have large interindividual variability and are dependent on several biometric factors. Personalized BP management aims to set specific BP targets for a given patient taking into account blood flow autoregulation and any history of chronic hypertension. To optimize cardiac output and oxygen delivery, individualized hemodynamic management based on functional assessment of fluid responsiveness is used. Innovative noninvasive technologies now enable preoperative assessment of a patient's personal normal hemodynamic values, which can then be targeted in the perioperative phase. In critically ill patients admitted to the ICU, adaptive multiparametric hemodynamic monitoring can help to personalize hemodynamic management.
Summary:
Personalized hemodynamic management targets personal normal values of hemodynamic variables, which are adjusted to biometric data and adapted to the clinical situation (i.e., adequate values). This approach optimizes cardiovascular dynamics based on the patient's personal hemodynamic profile.
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