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Related Concept Videos

Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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Related Experiment Video

Updated: Mar 1, 2026

Murine Model of CD40-activation of B cells
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Published on: March 5, 2010

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Correction: CD40 Activation Rescues Antiviral CD8+ T Cells from PD-1-Mediated Exhaustion.

Masanori Isogawa, Josan Chung, Yasuhiro Murata

    Plos Pathogens
    |June 1, 2017
    PubMed
    Summary

    This study corrects a previous article DOI. It ensures accurate citation for future research in the field.

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    Area of Science:

    • This study falls under the umbrella of scientific publishing and scholarly communication.

    Context:

    • The abstract serves to correct a previously published article's Digital Object Identifier (DOI).
    • Accurate DOIs are crucial for proper citation and retrieval of scientific literature.

    Purpose:

    • To provide the correct DOI for the article published in PLOS Pathogens.
    • To ensure readers and researchers can access the intended scientific content.

    Summary:

    • A correction is issued for the DOI of a scientific article.
    • The corrected DOI is essential for maintaining the integrity of the scientific record.

    Impact:

    • Ensures accurate referencing and citation of the scientific work.
    • Facilitates seamless access to the corrected article for the scientific community.