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DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
Published on: July 15, 2011
Leprosy in Southern Brazil: a twenty-year epidemiological profile
Ana Paula Nazario1,2, Jair Ferreira3,4, Lavínia Schuler-Faccini4,5,6
1Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.
Introduction::
This study evaluated leprosy rates in Rio Grande do Sul, an area with a historically low prevalence. However, recent studies are lacking.
Methods::
Data extracted from a National Database were analyzed for clinical features and compared to 1980s data. Tendency was assessed via stationarity analysis.
Results::
Between 1990 and 2011, 4,770 cases were reported (0.21/10,000 inhabitants; 95% CI = 0.19-0.24). Detection was slightly higher among males, 1.9% cases were among children and most multibacillary (74.7%) at diagnosis.
Conclusions::
Leprosy is controlled in RS, but most cases are multibacillary. Early identification is important to avoid disabilities due to late diagnosis.
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