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Genetics of Legionella pneumophila
1Department of Microbiology and Immunology, University of Miami School of Medicine, Florida 33101.
Abstract:
Legionella pneumophila is a facultative intracellular pathogen capable of entering and growing in a variety of phagocytic cells including free-living amoebae as well as alveolar macrophages and monocytes. A genetic analysis of L. pneumophila should facilitate the identification of bacterial factors that promote the intracellular lifestyle of this organism.