Related Experiment Video
Updated: Aug 30, 2026

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
Interactions between small viral RNAs of vesicular stomatitis virus and components of cellular gene expression
1Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.
Abstract:
Recent interest in the details of virus-host interactions has come to focus on molecular contacts between cell factors and components of viruses. These generally concern protein-protein and protein-nucleic acid interactions. In this review, protein-nucleic acid interactions involving viral transcription products and cell proteins are considered. Also examined here will be the hypothesis that such interactions have evolved because viruses have adopted cellular processes to favour their own replication and that the consequences of this co-evolution can be the disruption of the macromolecular functions of the cell, and eventual cytopathology. For its own survival in the long term, the host may evolve more refined mechanisms to evade the damage levied by the intruding virus.
Related Concept Videos
Retrovirus Life Cycles
Viral Recombination
siRNA - Small Interfering RNAs
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the ATP-dependent...
Size and Structure of Viral Genomes
Inhibitors Of Virion Release
Inhibitors of Virion Maturation and Assembly

