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Published on: September 10, 2020
POPULATION STRUCTURE AND DYNAMICS OF SELECTED GENES IN THE MOSQUITO CULEX PIPIENS
Christine Chevillon1, Nicole Pasteur1, Maïté Marquine1
1Institut des Sciences de l'Evolution (Centre National de la Recherche Scientifique, Unité de Recherche Associée 327), Laboratoire Génétique et Environnement, Université de Montpellier II (Case courrier 65), place Eugène Bataillon, 34095, Montpellier, France.
Abstract:
To determine the outcome of the combined effects of gene flow, genetic drift, and selection on the evolution of insecticide-resistance genes in the mosquito Culex pipiens, samples were collected along three transects crossing treated and nontreated areas in northern Spain and southern France. Electrophoretic polymorphisms of five presumably neutral genes disclosed that differentiation among samples was low, and that both Wright F-statistics and Slatkin private-alleles methods provided a high estimate for Nm. In contrast, there was a strong differentiation in the distribution of resistance genes closely associated with insecticide treatments. These divergent situations are explained in relation to both the very recent origin of some resistance genes that are still localized geographically (A2-B2 and C1), and the high fitness cost of the older and ubiquitous ones in nontreated areas (A1, A4-B4, and AceR ).
