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Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Chronic Inflammation
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Chronic Obstructive Pulmonary Disease-V: Management01:29

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Chronic Obstructive Pulmonary Disease01:24

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Methods for Detecting Cough and Airway Inflammation in Mice
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Post-infectious persistent cough: pathogenesis and therapeutic options.

Carlo Capristo1, Giovanni A Rossi2,3

  • 1Department of Woman and Child, General and Specialized Surgery, L. Vanvitelli University of Campania, Naples, Italy.

Minerva Pediatrica
|June 2, 2017
PubMed
Summary
This summary is machine-generated.

Persistent post-infectious cough, lasting over three weeks after an infection, causes significant discomfort and disrupts daily life. Current treatments offer limited effectiveness for this common respiratory symptom.

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Area of Science:

  • Respiratory Medicine
  • Infectious Diseases
  • Clinical Pharmacology

Background:

  • Post-infectious cough is a frequent complication following viral upper respiratory tract infections.
  • While typically self-limiting, a persistent cough lasting over three weeks can significantly impact quality of life.
  • The underlying mechanisms of cough regulation are increasingly understood, yet effective treatments remain limited.

Purpose of the Study:

  • To review the current understanding of persistent post-infectious cough.
  • To evaluate the efficacy of existing therapeutic strategies.
  • To identify potential areas for future treatment development.

Main Methods:

  • Literature review of studies on post-infectious cough.
  • Analysis of clinical data on cough duration and associated symptoms.
  • Assessment of pharmacological and non-pharmacological interventions.

Main Results:

  • Persistent post-infectious cough is characterized by throat irritation and paroxysmal coughing.
  • This condition can lead to considerable morbidity, interfering with daily activities.
  • Current therapeutic options demonstrate limited or moderate effectiveness.

Conclusions:

  • Despite advances in understanding cough physiology, effective treatments for persistent post-infectious cough are lacking.
  • Further research is needed to develop more effective interventions for this common condition.
  • Addressing the impact of persistent cough on patient well-being is crucial.