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Ischemic Heart Disease: Overview01:17

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Transient ischemic attack and ischemic stroke patients with or without prior stroke.

F Buchwald1, B Norrving1, J Petersson1

  • 1Department of Clinical Sciences Lund, Neurology, Lund University, Skåne University Hospital, Lund/Malmö, Sweden.

Acta Neurologica Scandinavica
|June 2, 2017
PubMed
Summary

Patients with a history of stroke have more vascular risk factors. However, oral anticoagulant treatment for atrial fibrillation is underutilized in these stroke patients.

Keywords:
atrial fibrillationcerebrovascular diseaseshistory of strokeischemic strokesecondary preventiontransient ischemic attack

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Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • A history of stroke is frequent in patients experiencing transient ischemic attack (TIA) and ischemic stroke (IS).
  • Characterizing this patient group is crucial for understanding stroke recurrence and prevention strategies.

Purpose of the Study:

  • To compare the characteristics, risk factors, and secondary preventive treatments in patients with TIA or IS who have versus those who do not have a prior stroke history.

Main Methods:

  • Utilized hospital-based data from the Swedish Stroke Register (Riksstroke) for TIA and IS events between July 2011 and June 2013.
  • Analyzed patient demographics, comorbidities, and medication use, comparing those with and without a history of stroke.

Main Results:

  • A history of stroke was present in 19.3% of TIA and 24.6% of IS patients.
  • Patients with prior stroke were older, more male, and had higher rates of atrial fibrillation, hypertension, and diabetes.
  • While antihypertensive use was higher in patients with prior stroke, oral anticoagulant (OAC) use for atrial fibrillation was lower compared to those without a prior stroke.

Conclusions:

  • Vascular risk factors are more prevalent in TIA and IS patients with a history of stroke.
  • Oral anticoagulant (OAC) treatment for atrial fibrillation is underutilized in stroke patients with a history of stroke, indicating a gap in secondary prevention.