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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
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Transient ischemic attack and ischemic stroke patients with or without prior stroke
F Buchwald1, B Norrving1, J Petersson1
1Department of Clinical Sciences Lund, Neurology, Lund University, Skåne University Hospital, Lund/Malmö, Sweden.
Acta Neurologica Scandinavica
|June 2, 2017
Summary
Patients with a history of stroke have more vascular risk factors. However, oral anticoagulant treatment for atrial fibrillation is underutilized in these stroke patients.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- A history of stroke is frequent in patients experiencing transient ischemic attack (TIA) and ischemic stroke (IS).
- Characterizing this patient group is crucial for understanding stroke recurrence and prevention strategies.
Purpose of the Study:
- To compare the characteristics, risk factors, and secondary preventive treatments in patients with TIA or IS who have versus those who do not have a prior stroke history.
Main Methods:
- Utilized hospital-based data from the Swedish Stroke Register (Riksstroke) for TIA and IS events between July 2011 and June 2013.
- Analyzed patient demographics, comorbidities, and medication use, comparing those with and without a history of stroke.
Main Results:
- A history of stroke was present in 19.3% of TIA and 24.6% of IS patients.
- Patients with prior stroke were older, more male, and had higher rates of atrial fibrillation, hypertension, and diabetes.
- While antihypertensive use was higher in patients with prior stroke, oral anticoagulant (OAC) use for atrial fibrillation was lower compared to those without a prior stroke.
Conclusions:
- Vascular risk factors are more prevalent in TIA and IS patients with a history of stroke.
- Oral anticoagulant (OAC) treatment for atrial fibrillation is underutilized in stroke patients with a history of stroke, indicating a gap in secondary prevention.
