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Patient-reported outcomes (PROs) in chronic urticaria
Kristian Moestrup1, Misbah N Ghazanfar1, Simon F Thomsen1,2
1Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.
International Journal of Dermatology
|June 2, 2017
Summary
Chronic urticaria, a persistent itchy skin condition, significantly impacts daily life. Patient-reported outcomes (PROs) are vital for monitoring this disease due to the lack of reliable biomarkers for chronic spontaneous urticaria.
Area of Science:
- Dermatology
- Clinical Research
Background:
- Chronic urticaria is an itchy skin disease lasting over 6 weeks.
- Its fluctuating nature complicates disease monitoring and treatment.
- No reliable biomarkers exist for measuring chronic spontaneous urticaria activity.
Purpose of the Study:
- To provide an overview of patient-reported outcomes (PROs) for chronic urticaria.
- To highlight the strengths and limitations of seven different PROs.
- To discuss the use of PROs in clinical practice and research for chronic urticaria.
Main Methods:
- Literature review of patient-reported outcomes (PROs).
- Analysis of seven distinct PROs used in chronic urticaria research.
- Evaluation of PROs for disease activity, control, and quality of life assessment.
Main Results:
- Seven patient-reported outcomes (PROs) are identified for chronic urticaria assessment.
- Each PRO has unique strengths and limitations for clinical use.
- PROs are crucial for evaluating disease activity, control, and quality of life in chronic urticaria.
Conclusions:
- Patient-reported outcomes (PROs) are essential tools for managing chronic urticaria.
- The selection of appropriate PROs is critical for effective patient care and research.
- Further research should focus on optimizing PRO utilization in chronic urticaria.
