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Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

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An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
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ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

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Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
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Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

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The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
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Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

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Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
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Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

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The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
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Related Experiment Video

Updated: Mar 1, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Electrocardiographic Changes After Suicidal Digoxin Intoxication in a Healthy Woman.

Natalia Lorenzo Muñoz1, Amparo Benedicto Buendía1, Fernando Alfonso Manterola1

  • 1Department of Cardiology, Hospital Universitario de La Princesa, Madrid, Spain.

The Open Cardiovascular Medicine Journal
|June 3, 2017
PubMed
Summary

Suicidal digoxin overdose is rare but requires prompt recognition of ECG changes for treatment. This case highlights successful conservative management through close monitoring of ECG and digoxin levels.

Keywords:
(CT) scanDigoxinElectrocardiogram (ECG)Multiple arrhythmiasMyocardial necrosis

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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Area of Science:

  • Cardiology
  • Clinical Toxicology

Background:

  • Suicidal digoxin intoxication is an uncommon but serious clinical scenario.
  • Early recognition of specific electrocardiographic (ECG) changes is crucial for timely intervention.

Observation:

  • A case of massive digoxin ingestion resulting in suicidal attempt is presented.
  • The patient was managed conservatively with intensive clinical surveillance.

Findings:

  • Conservative management involved close monitoring of evolving ECG patterns.
  • Serial digoxin serum level measurements guided the treatment strategy.
  • The patient achieved a satisfactory outcome with this approach.

Implications:

  • This case underscores the importance of clinical suspicion in diagnosing digoxin toxicity.
  • Conservative management, guided by ECG and serum levels, can be effective for suicidal digoxin overdose.
  • Effective management relies on vigilant monitoring and prompt interpretation of diagnostic data.