Related Experiment Video
Updated: Mar 1, 2026

Isolation and Analysis of Aortic Arch and Root Lesions in an Atherosclerotic Mouse Model
Published on: February 14, 2025
[Calcification of atherosclerotic plaques and assessment of their stability]
I M Ignat'ev1, Iu A Chelyshev2, A V Zanochkin1
1Interregional Clinical and Diagnostic Centre, Course of Cardiovascular Surgery, Kazan State Medical University of the RF Health Ministry, Kazan, Russia.
Abstract:
Presented herein is a review of the literature concerning mechanisms of calcification of atherosclerotic plaques (ASP), showing molecular mechanisms of interaction of processes of calcification with the factors inducing instability of ASPs (anti-inflammatory cytokines, neoangiogenesis, increased level of matrix metalloproteinases, etc.), also describing the effect of the value of volume of scope of calcification on stability of ASPs, followed by discussing the problems related to the role of biominerals (hydroxyapatite calcium phosphate) and Mn2+ in calcification of ASPs and their impact upon stability of the plaque.
More Related Videos
08:02Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
Published on: November 15, 2024
13:07Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Related Concept Videos
Atherosclerosis I: Introduction
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Coronary Artery Disease II: Pathophysiology
Inflammation
Coronary Artery Disease I: Introduction