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Published on: September 15, 2023
ECMO and cytokine removal for bridging to surgery in a patient with ischemic ventricular septal defect - a case
Stefanie Marek1,2, Gunnar Gamper1,2, Georg Reining1,2
1Karl Landsteiner Society - Institute for Research in Ischemic Heart Disease and Arrhythmias, St. Pölten - Austria.
Insights
Postinfarction ventricular septal defect (VSD) is a lethal complication. Veno-arterial extracorporeal membrane oxygenation with blood purification bridged a patient to surgical VSD closure, managing cardiogenic shock.
Area of Science:
- Cardiology
- Intensive Care Medicine
- Cardiovascular Surgery
Background:
- Postinfarction ventricular septal defect (VSD) is a rare but severe complication of myocardial infarction.
- Optimal management strategies, including timing of surgical repair and use of mechanical circulatory support, are debated.
- An interdisciplinary approach is crucial for managing these high-risk patients.
Observation:
- A patient presented with cardiogenic shock secondary to an ischemic VSD after a posterior myocardial infarction.
- The patient was treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and extracorporeal blood purification therapy (CytoSorb®).
Findings:
- This combined therapy served as a successful bridge to definitive surgical closure of the VSD.
- The patient's cardiogenic shock was effectively managed during the bridging period.
Implications:
- This case highlights the potential utility of VA-ECMO combined with blood purification as a temporizing measure in ischemic VSD.
- Such an approach may improve outcomes by stabilizing patients for subsequent surgical intervention.
- Further research is warranted to establish the role of this strategy in managing postinfarction VSD.
Abstract:
Even in the modern era of percutaneous coronary intervention, postinfarction ventricular septal defect (VSD) remains a serious and often lethal complication. Whether or not immediate surgical repair or delaying surgery a few days aided by intra-aortic counterpulsation provides the optimal strategy remains a matter of debate. An interdisciplinary approach of intensivists and cardiac surgeons in this setting is mandatory. We report the use of veno-arterial extracorporeal membrane oxygenation and extracorporeal blood purification therapy (CytoSorb®) as bridging to surgical closure in a patient with an ischemic VSD leading to protracted cardiogenic shock after posterior myocardial infarction.
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