ECMO and cytokine removal for bridging to surgery in a patient with ischemic ventricular septal defect - a case

Stefanie Marek1,2, Gunnar Gamper1,2, Georg Reining1,2

  • 1Karl Landsteiner Society - Institute for Research in Ischemic Heart Disease and Arrhythmias, St. Pölten - Austria.

Insights

Postinfarction ventricular septal defect (VSD) is a lethal complication. Veno-arterial extracorporeal membrane oxygenation with blood purification bridged a patient to surgical VSD closure, managing cardiogenic shock.

Area of Science:

  • Cardiology
  • Intensive Care Medicine
  • Cardiovascular Surgery

Background:

  • Postinfarction ventricular septal defect (VSD) is a rare but severe complication of myocardial infarction.
  • Optimal management strategies, including timing of surgical repair and use of mechanical circulatory support, are debated.
  • An interdisciplinary approach is crucial for managing these high-risk patients.

Observation:

  • A patient presented with cardiogenic shock secondary to an ischemic VSD after a posterior myocardial infarction.
  • The patient was treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and extracorporeal blood purification therapy (CytoSorb®).

Findings:

  • This combined therapy served as a successful bridge to definitive surgical closure of the VSD.
  • The patient's cardiogenic shock was effectively managed during the bridging period.

Implications:

  • This case highlights the potential utility of VA-ECMO combined with blood purification as a temporizing measure in ischemic VSD.
  • Such an approach may improve outcomes by stabilizing patients for subsequent surgical intervention.
  • Further research is warranted to establish the role of this strategy in managing postinfarction VSD.